Modern approaches to studying the antimicrobial and antifungal activities of new 1,2,4-triazole derivatives

نویسندگان

چکیده

1,2,4-Triazole and its derivatives are a promising class of organic compounds. For long time, they remain in the spotlight due to number unique properties: high ability chemical transformations, presence various types biological activity and, course, low toxicity. Also, 1,2,4-triazole currently well studied implemented spheres human life as effective drugs, plant protection products (growth stimulants, fungicides, herbicides), anti-corrosion materials, plasticizers, etc.
 The aim work was analyze systematize new data on antimicrobial antifungal select area ??research based accumulation large amount information properties derivatives.
 analysis modern sources recent years argues proves prospects for finding biologically active compounds derivatives. obtained clearly indicates possibility using 1,2,4-triazoles, which contain Sulfur atom, objects study.
 is one most well-known classes compounds, has wide range action. Derivatives characterized by antibacterial, antifungal, hypoglycemic, antihypertensive, analgesic, anti-inflammatory, antitumor, antiviral activities. trend creating drugs growing.
 Some derivatives: ribavirin (an agent), risatriptan (a selective 5HT1 serotonin receptor agonist), alprazolam anxiolytic fluconazole, itraconazole (antifungal drugs). this compound have proven themselves veterinary medicine. Drugs such Avesstim, Trifuzol, Trifuzol-neo immunostimulants dosage forms (1%, 2% solutions, suppositories) used farms, private livestock sector pets.
 These facts best example understanding molecules among

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ژورنال

عنوان ژورنال: Farmatsevtychnyi? zhurnal

سال: 2022

ISSN: ['0367-3057', '2617-9628']

DOI: https://doi.org/10.32352/0367-3057.3.22.11